Welcome to PARS, a server for the prediction of allosteric and regulatory sites on protein structures. PARS queries protein dynamics and structural conservation to identify pockets that may exert a regulatory effect upon binding of a small-molecule ligand.

  • Click here to run a prediction,

  • or if you prefer, check out a tutorial before getting started.

  • If you find this server useful please cite:
    PARS: a web server for the prediction of Protein Allosteric and Regulatory Sites
    Panjkovich A, Daura X.
    Bioinformatics. 2014 May 1;30(9):1314-5.

    This project has been supported by funding under the Seventh Research Framework Programme of the European Union
    (ref. HEALTH-F3-2009-223101, AntiPathoGN)